WHY CHOOSE RS-75 Hot cell

  • GMP conformity: meets the good manufacturing practice standards
  • Filtration: air quality Class C in accordance with ISO standard 14644-1, HEPA filters (inlet) / HEPA + active charcoal (outlet)
  • Sealing: sealing class 3 in accordance with ISO standard 10648
  • Compatibility: with the most of synthesis modules on the market


The RS-75 shielded hot cell is designed to hold, in addition to the radiosynthesis robots, the equipment required for research into new radiopharmaceutical applications.

The RS-75 isolator perfectly complies with statutory requirements, for good pharmaceutical practice and those set out in radiation protection standards.

RS-75 Hot cell: complete safety and ease-of-use

They feature a high-standard 316L stainless steel interior finish, radial angles and smooth surfaces allowing for easy cleaning.

The hot cell is equipped with a fully removable stainless steel sliding tray for easy installation and connection of the synthesis module and its accessories.
The tray is also used as a drip tray in the event of liquid dispersion.
Each hot cell features liquid or gaseous target tube inlets, and different types of electric and fluidic connectors (nitrogen, hydrogen, compressed air, etc.). This isolator meets the requirements of the operators.

Designed to reduce exposure to the minimum

It has a vial exit, accessible from the work surface thanks to its shielded ball joint and handling tongs.
The exit allows the vials to be placed in transport container with no containment breach.
The container covers are automatically closed when exiting the cell. Finally, it can be equipped with leaktight penetrations for the daily passage of the sterile line tube to the dispensing hot cell.

The hot cell is depressurised using automatic opening valves connecting to the nuclear ventilation network of the building or the Gas Compression System (GCS) for use in static containment.
A pressure gauge continuously displays the negative pressure value in the hot cell.

All the functions of the isolator are controlled on a touch screen:

  • inflating of the seals,
  • lighting,
  • ventilation valve control, etc.

The screen also continuously displays the irradiation values and negative pressure inside the hot cell.

Other possible configurations:

  • 100 mm shielding
  • HEPA filtration
  • Active charcoal at inlet and outlet…

*Compliant with the French Nuclear Safety Authority (ASN) requirements


  • Overall dimensions: L 1,665 x D 1,454 x H 2,380 mm
  • Cell empty weight: 9,000 kg
  • Exterior finish: 304L brushed stainless steel
  • Interior finish: 316L stainless steel
  • Standard equipment:
    - 1 radiosynthesis compartment equipped with a shielded door
    - 1 non-shielded solvent compartment
    - 1 vial exit including a shielded ball joint fitted with its remote handling tongs
  • Connection to the nuclear ventilation network: DN50
  • General power supply voltage: 230 V / 16 A
  • Floor load: 10 tons/m²


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