Theranojet®ARA

Theranojet®^ARA is an injection pump shield designed for the radiation protected intravenous administration of radiopharmaceutical drugs for RadioPharmaceutical Therapy (RPT) labelled in particular with ¹⁷⁷Lu.

Lightweight, mobile and versatile, the Theranojet®^ARA pump injection shield allows the user to safely load radiopharmaceuticals using a removable shielded container. It facilitates transport and loading of the vial within the hot lab while reducing the risk of contamination to a minimum.

Designed for optimal radiation protection

Theranojet®^ARA guarantees patient complete protection administration. Its secure and configurable infusion pump can detect occlusions or air bubbles. As a result, it guarantees flexibility according to the different protocols used. It prevents any risk of extravasation or the injection or air bubbles.

This lightweight unit with 4 castor wheels, is easy to handle and move around. Its two side handles allow it to be moved effortlessly to carry patient doses to the injection cubicles.

It is made entirely of stainless steel and includes a removable containment tray. Allowing for simple and quick microbiological or radioactive decontamination, when required, without altering the injection shield components.

Theranojet®^ARA components

• Intravenous bag holders are designed to suspend solute bags and facilitate dose dilution as well as IV tube rinsing.

• The support and vial shield enables the vial to be inverted, ensuring that all the content is fully administered. This system allows direct loading of the therapy vial using a needleless transfer device. This reduces the risk of contamination, needle stick injuries and allows for a safe location for the dose to decay.

• A removable containment tray makes it possible to contain the radiopharmaceutical in the event of a connection problem between the vial and the needleless transfer device. The tray is non-porous and easily removable, making microbiological and radioactive decontamination easier.

• The dual-line pump has an adjustable screen allowing the user to easily visualize and program the infusion settings. Dual channels allow the vial to be rinsed ‘hands-free’ using the second line to ensure the entire radiopharmaceutical dose is administered to the patient with little to no residual. During infusion, the pump will alert for any occlusions, extravasations or air bubbles, as well as indicate remaining volume to be infused. The two lines of the pump enable a more gradual injection of the radiopharmaceutical with optimal operator radiation protection while improving the patient comfort and treatment toleranceIts curved shape provides radiation protection for the user in a standing position, ensuring maximum protection for the areas most sensitive to radiation, such as the lens of the eye. For optimal comfort, the pump is installed at an ergonomic height, allowing the operator to use it naturally, effortlessly and without awkward postures. This avoids the need to bend over, thus preserving the operator’s health and efficiency by reducing the risk of musculoskeletal disorders (MSDs).

• The upper shielding protects the user during the injection. The transparency of shielded organic glass makes the tubing and the retention area visible, yet still accessible throughout the operation. The glass and shield are on a hinge, allowing the user to easily access the vial or tubing.

• The side handles make it easy to guide the device. It has a large gripping area that can be adjusted to the height of the healthcare personnel.

• The tubing holder ensures a firm and reliable hold on the tube, eliminating any risk of accidental disconnection. Designed to meet the most stringent requirements of nuclear medicine, it guarantees perfect circuit continuity, enhancing both procedural safety and radiation protection for operators.

• The lower containment tray prevents any risk of leakage in the event of a problem during pump handling. The tray is smooth and removable, facilitating microbiological and radioactive decontamination.

• The 4 castor wheels make it easy to move the device. It is possible to lock the wheels to ensure that the device cannot be moved.

Theranojet®^ARA integrated equipments:

• Injection pump
• Patient injection kit
• Shielded vial shield

Theranojet®^ARA preparation equipment

• The shielded vial connection installation device is specially designed to secure the critical step of inserting the spike into the vial. Thanks to its integrated push button, it allows for precise, stable and effortless insertion, thereby reducing the risks of direct manual handling. Used within a shielded hot cell, it offers optimal protection for the operator while ensuring the compliance and reliability of the injection kit installation.
• The vial connection removal tong ensures safe removal of the spike at the end of injection, while minimising effort and risky movements for the operator
• The shielded cover for vial decay is specially designed to ensure safe storage and decay of the vial at the end of injection. Perfectly suited to the shielded pots used in RadioLigand Therapy (RLT) procedures, it offers optimal protection against radiation.

This shield can be used for singledose and progressively fractionable injections and can be extended to other uses such as other uses such as alpha therapy, and some diagnostic protocols in nuclear medicine.

Theranojet®ARA paves the way for targeted therapy, which precisely eliminates cancer cells while preserving surrounding healthy tissue. This personalised approach, also known as theranostics, an innovative combination of therapy and diagnosis, maximises the chances of treatment success while reducing undesirable side effects, offering new perspectives in the fight against cancer.

Developed in collaboration with the Parisian Beaujon AP-HP (Assistance Publique – Hôpitaux de Paris) Hospital.

Discover our article about the 1st Lutetium-177 injections with the Theranojet®ARA at the Beaujon AP-HP hospital